Myelodysplastic syndromes (MDS) mainly occur in the elderly but can affect younger individuals too. The latter require special consideration to identify suitable candidates for allogeneic stem-cell transplantation, a potentially curative approach carrying a high risk of treatment-related complications.
Department of Hematology, Oncology, and Clinical Immunology, and Institute of Human Genetics, Heinrich-Heine-University, Duesseldorf, Germany. kuendgen@med.uni-duesseldorf.de