| pubmed-article:17082961 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17082961 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:17082961 | lifeskim:mentions | umls-concept:C0029418 | lld:lifeskim |
| pubmed-article:17082961 | lifeskim:mentions | umls-concept:C0222677 | lld:lifeskim |
| pubmed-article:17082961 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:17082961 | lifeskim:mentions | umls-concept:C0016126 | lld:lifeskim |
| pubmed-article:17082961 | lifeskim:mentions | umls-concept:C0600430 | lld:lifeskim |
| pubmed-article:17082961 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:17082961 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:17082961 | pubmed:dateCreated | 2007-10-10 | lld:pubmed |
| pubmed-article:17082961 | pubmed:abstractText | An early response to mechanical stimulation of bone cells in vitro is an increase in intracellular calcium concentration ([Ca (2+)](i)). This study analyzed the [Ca (2+)](i) wave area, magnitude, duration, rise time, fall time, and time to onset in individual osteoblasts for two identical bouts of mechanical stimulation separated by a 30-min rest period. The area under the [Ca (2+)](i) wave increased in the second loading bout compared to the first. This suggests that rest periods may potentiate mechanically induced intracellular calcium signals. Furthermore, many of the [Ca (2+)](i) wave parameters were strongly, positively correlated between the two bouts of mechanical stimulation. For example, in individual primary osteoblasts, if a cell had a large [Ca (2+)](i) wave area in the first bout it was likely to have a large [Ca (2+)](i) wave area in the second bout (r (2) = 0.933). These findings support the idea that individual bone cells have "calcium fingerprints" (i.e., a unique [Ca (2+)](i) wave profile that is reproducible for repeated exposure to a given stimulus). | lld:pubmed |
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| pubmed-article:17082961 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17082961 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17082961 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17082961 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17082961 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17082961 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:17082961 | pubmed:issn | 1617-7959 | lld:pubmed |
| pubmed-article:17082961 | pubmed:author | pubmed-author:DonahueHenry... | lld:pubmed |
| pubmed-article:17082961 | pubmed:author | pubmed-author:JacobsChristo... | lld:pubmed |
| pubmed-article:17082961 | pubmed:author | pubmed-author:DonahueSeth... | lld:pubmed |
| pubmed-article:17082961 | pubmed:author | pubmed-author:SuzukiSakikoS | lld:pubmed |
| pubmed-article:17082961 | pubmed:author | pubmed-author:GodinLindsay... | lld:pubmed |
| pubmed-article:17082961 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17082961 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:17082961 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17082961 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17082961 | pubmed:pagination | 391-8 | lld:pubmed |
| pubmed-article:17082961 | pubmed:dateRevised | 2010-9-15 | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
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| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:meshHeading | pubmed-meshheading:17082961... | lld:pubmed |
| pubmed-article:17082961 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17082961 | pubmed:articleTitle | Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction. | lld:pubmed |
| pubmed-article:17082961 | pubmed:affiliation | Department of Mechanical Engineering-Engineering Mechanics, Michigan Technological University, Houghton, MI 49931, USA. | lld:pubmed |
| pubmed-article:17082961 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17082961 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:17082961 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17082961 | lld:pubmed |
