Natural killer (NK) cells are the most abundant lymphocyte population at the maternal-fetal interface. They are suggested to be important during placentation by controlling trophoblast invasion. If placentation is suboptimal, pre-eclampsia can occur.
Aberrant uterine natural killer (NK)-cell expression and altered placental and serum levels of the NK-cell promoting cytokine interleukin-12 in pre-eclampsia.
Arrhenius Laboratories for Natural Sciences, Department of Immunology, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden. nora.bachmayer@imun.su.se