| pubmed-article:17027512 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17027512 | lifeskim:mentions | umls-concept:C0444626 | lld:lifeskim |
| pubmed-article:17027512 | lifeskim:mentions | umls-concept:C0961814 | lld:lifeskim |
| pubmed-article:17027512 | pubmed:dateCreated | 2006-10-9 | lld:pubmed |
| pubmed-article:17027512 | pubmed:abstractText | Interleukin-22 (IL-22) is a cytokine that regulates the production of acute phase proteins of the immunological response. On binding to its cognate receptor (IL-22R1), which is associated to the interleukin-10 receptor 2 (IL-10R2), IL-22 promotes activation of signal transducer and activator of transcription (STAT) pathway and several other cellular responses. A soluble receptor termed interleukin-22 binding protein (IL-22BP) is also able to bind to IL-22 as a natural protein antagonist, and probably provides systemic regulation of IL-22 activity. This inflammatory response system is analyzed here in terms of its molecular physiology and structural assembly. Three-dimensional (3D) model of IL-22 and structural basis of its interactions with the cognate receptors are discussed. | lld:pubmed |
| pubmed-article:17027512 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17027512 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17027512 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17027512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17027512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17027512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17027512 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17027512 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17027512 | pubmed:issn | 0083-6729 | lld:pubmed |
| pubmed-article:17027512 | pubmed:author | pubmed-author:Ferreira... | lld:pubmed |
| pubmed-article:17027512 | pubmed:author | pubmed-author:PolikarpovIgo... | lld:pubmed |
| pubmed-article:17027512 | pubmed:author | pubmed-author:RenauldJean-C... | lld:pubmed |
| pubmed-article:17027512 | pubmed:author | pubmed-author:DumoutierLaur... | lld:pubmed |
| pubmed-article:17027512 | pubmed:author | pubmed-author:NagemRonaldo... | lld:pubmed |
| pubmed-article:17027512 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17027512 | pubmed:volume | 74 | lld:pubmed |
| pubmed-article:17027512 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17027512 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17027512 | pubmed:pagination | 77-103 | lld:pubmed |
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| pubmed-article:17027512 | pubmed:meshHeading | pubmed-meshheading:17027512... | lld:pubmed |
| pubmed-article:17027512 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:17027512 | pubmed:articleTitle | Interleukin-22 and its crystal structure. | lld:pubmed |
| pubmed-article:17027512 | pubmed:affiliation | Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627 CEP 31270910, Belo Horizonte, MG, Brazil. | lld:pubmed |
| pubmed-article:17027512 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17027512 | pubmed:publicationType | Review | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17027512 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17027512 | lld:pubmed |
