Linked Life Data

17026467

Source:http://linkedlifedata.com/resource/pubmed/id/17026467

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pubmed-article:17026467pubmed:abstractTextHuman prominin-1 (CD133 or AC133) is an important cell surface marker used to isolate primitive hematopoietic stem cells. The commercially available antibody to human prominin-1 does not recognize rhesus prominin-1. Therefore, we isolated, cloned and characterized the complementary DNA (cDNA) of rhesus prominin-1 gene and determined its coding potential. Following the nomenclature of prominin family of genes, we named this cDNA as rhesus prominin-1.s1. The amino acid sequence data of the putative rhesus prominin-1.s1 could be used in designing antigenic peptides to raise antibodies for use in isolation of pure populations of rhesus prominin-1(+) hematopoietic cells. To the best of our knowledge, there has been no previously published report about the isolation of a prominin-1 cDNA from rhesus monkey (Macaca mulatta).lld:pubmed
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pubmed-article:17026467pubmed:year2006lld:pubmed
pubmed-article:17026467pubmed:articleTitleIsolation, molecular cloning and in vitro expression of rhesus monkey (Macaca mulatta) prominin-1.s1 complementary DNA encoding a potential hematopoietic stem cell antigen.lld:pubmed
pubmed-article:17026467pubmed:affiliationDivision of Stem Cell Transplantation, Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. syed.husain@stjude.orglld:pubmed
pubmed-article:17026467pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17026467pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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