| pubmed-article:17021609 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17021609 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:17021609 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:17021609 | lifeskim:mentions | umls-concept:C0019004 | lld:lifeskim |
| pubmed-article:17021609 | lifeskim:mentions | umls-concept:C0026565 | lld:lifeskim |
| pubmed-article:17021609 | lifeskim:mentions | umls-concept:C1520059 | lld:lifeskim |
| pubmed-article:17021609 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:17021609 | pubmed:dateCreated | 2006-11-2 | lld:pubmed |
| pubmed-article:17021609 | pubmed:abstractText | Intravenous vitamin D is standard therapy for secondary hyperparathyroidism in hemodialysis (HD) patients. In for-profit dialysis clinics, mortality was higher for patients on calcitriol compared to paricalcitol. Doxercalciferol, a second vitamin D2 analog, is currently available. We assessed mortality associated with each vitamin D analog and with lack of vitamin D therapy in patients who began HD at Dialysis Clinic Inc. (DCI), a not-for-profit dialysis provider. During the 1999-2004 study period we studied 7731 patients (calcitriol: n=3212; paricalcitol: n=2087; doxercalciferol: n=2432). Median follow-up was 37 weeks. Mortality rates (deaths/100 patient-years) were identical in patients on doxercalciferol (15.4, 95% confidence interval (13.6-17.1)) and paricalcitol (15.3 (13.6-16.9)) and higher in patients on calcitriol (19.6 (18.2-21.1)) (P<0.0001). In all models mortality was similar for paricalcitol versus doxercalciferol (hazard ratios=1.0). In unadjusted models, mortality was lower in patients on doxercalciferol (0.80 (0.66, 0.96)) and paricalcitol (0.79 (0.68, 0.92)) versus calcitriol (P<0.05). In adjusted models, this difference was not statistically significant. In all models mortality was higher for patients who did not receive vitamin D versus those who did (1.2 (1.1-1.3)). Mortality in doxercalciferol- and paricalcitol-treated patients was virtually identical. Differences in survival between vitamin D2 and D3 may be smaller than previously reported. | lld:pubmed |
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| pubmed-article:17021609 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:17021609 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17021609 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17021609 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:17021609 | pubmed:issn | 0085-2538 | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:JohnsonH KHK | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:ZagerP GPG | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:MeyerK BKB | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:HuntW CWC | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:StidleyC ACA | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:BedrickE JEJ | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:TentoriFF | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:Medical... | lld:pubmed |
| pubmed-article:17021609 | pubmed:author | pubmed-author:RohrscheibM... | lld:pubmed |
| pubmed-article:17021609 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17021609 | pubmed:volume | 70 | lld:pubmed |
| pubmed-article:17021609 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17021609 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17021609 | pubmed:pagination | 1858-65 | lld:pubmed |
| pubmed-article:17021609 | pubmed:dateRevised | 2007-12-19 | lld:pubmed |
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| pubmed-article:17021609 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:17021609 | pubmed:articleTitle | Mortality risk among hemodialysis patients receiving different vitamin D analogs. | lld:pubmed |
| pubmed-article:17021609 | pubmed:affiliation | Dialysis Clinic Inc., Albuquerque, New Mexico, USA. | lld:pubmed |
| pubmed-article:17021609 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17021609 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:17021609 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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