Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism.

Source:http://linkedlifedata.com/resource/pubmed/id/17015723

J. Immunol. 2006 Oct 15 177 8 5377-85

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17015723