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pubmed-article:17002626pubmed:abstractTextHydroxyethyl starch (HES) solutions have largely replaced conventional plasma expanders such as human albumin and colloidal fluids. Only a few side effects have been reported and mainly concern pruritus or blood coagulation disorders. Excessive HES exposure can result in diffuse tissue storage and accumulation with foamy appearing macrophages which produce the enzyme chitotriosidase (CT). In case of massive tissue storage, this enzyme activity can reach levels comparable to those of Gaucher disease.lld:pubmed
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pubmed-article:17002626pubmed:articleTitleAcquired lysosomal storage caused by frequent plasmapheresis procedures with hydroxyethyl starch.lld:pubmed
pubmed-article:17002626pubmed:affiliationDepartment of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands. jja.auwerda@ikazia.nllld:pubmed
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