| pubmed-article:1696729 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1179435 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1167162 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C0162795 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C0041525 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1145667 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1510827 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C0392762 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
| pubmed-article:1696729 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
| pubmed-article:1696729 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:1696729 | pubmed:dateCreated | 1990-9-20 | lld:pubmed |
| pubmed-article:1696729 | pubmed:abstractText | Many RNA-associated proteins contain a ribonucleoprotein (RNP) consensus octamer encompassed by a conserved 80 amino acid sequence, which we have termed an RNA recognition motif (RRM). RRM family members contain either one (class I) or multiple (class II) copies of this motif. We report here that a class II component of the U1 small nuclear RNP (snRNP), the A protein of U1 snRNP (U1snRNP-A), contains two RRMs (RRM1 and -2), yet has only one binding domain (RRM1) that interacts specifically with stem-loop II of U1 RNA. Quantitative analysis of binding affinities of fragments of U1snRNP-A demonstrated that an 86-amino acid polypeptide was competent to bind to U1 RNA with an affinity comparable to that of the full-length protein (Kd approximately 80 nM). The carboxyl-terminal RRM2 of U1snRNP-A did not bind to U1 RNA and may recognize an unidentified heterologous RNA. We propose that class II proteins may function as bridges between RNA components of RNP complexes such as the spliceosome. | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1696729 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1696729 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696729 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1696729 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1696729 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:1696729 | pubmed:author | pubmed-author:KeeneJ DJD | lld:pubmed |
| pubmed-article:1696729 | pubmed:author | pubmed-author:QueryC CCC | lld:pubmed |
| pubmed-article:1696729 | pubmed:author | pubmed-author:Lutz-Freyermu... | lld:pubmed |
| pubmed-article:1696729 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1696729 | pubmed:volume | 87 | lld:pubmed |
| pubmed-article:1696729 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1696729 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1696729 | pubmed:pagination | 6393-7 | lld:pubmed |
| pubmed-article:1696729 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:meshHeading | pubmed-meshheading:1696729-... | lld:pubmed |
| pubmed-article:1696729 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:1696729 | pubmed:articleTitle | Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA. | lld:pubmed |
| pubmed-article:1696729 | pubmed:affiliation | Department of Microbiology and Immunology, Duke University Medical Center, Durham, NC 27710. | lld:pubmed |
| pubmed-article:1696729 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:6626 | entrezgene:pubmed | pubmed-article:1696729 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1696729 | lld:pubmed |
