| pubmed-article:16933259 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16933259 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:16933259 | lifeskim:mentions | umls-concept:C0043117 | lld:lifeskim |
| pubmed-article:16933259 | pubmed:issue | 5 Suppl | lld:pubmed |
| pubmed-article:16933259 | pubmed:dateCreated | 2006-8-31 | lld:pubmed |
| pubmed-article:16933259 | pubmed:abstractText | Idiopathic thrombocytopenic purpura in children remits spontaneously in the majority of cases but most children require treatment. Between 1995 and 2005, 265 children (0-15 years old) have been consecutively observed and treated: 28 children with high doses of methylprednisolone (HDMP) (15 mg/kgx4 days), 63 with HDMP (7.5 mg/kgx4 days), 37 with HD dexamethasone (DXM) pulses, 29 with low doses of MP, and 51 with different doses of intravenous immunoglobulins (IVIG) (0.4 or 0.8 g/kg). Fifty-seven children have not been treated because of a platelet count>or=10x10(9)/L and no significant bleeding. Two hundred forty-four (92.1%) children reached a persistent CR, 237 (89.4%) after a first-line treatment or the wait and see strategy. No statistically significant differences in CR related to different treatments have been observed. IVIG and HDMP (7.5 mg/kg for 4 days) are the best treatments to reach quickly safe platelet levels>or=30x10(9)/L (3-6 days) and CR (7-11 days). Among non-responding (NR) patients, seven have been splenectomized and three reached stable CR. These results emphasize differences with adult ITP. | lld:pubmed |
| pubmed-article:16933259 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16933259 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16933259 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16933259 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16933259 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:16933259 | pubmed:issn | 1545-5009 | lld:pubmed |
| pubmed-article:16933259 | pubmed:author | pubmed-author:CarusoRoberta... | lld:pubmed |
| pubmed-article:16933259 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:16933259 | pubmed:author | pubmed-author:PansiniValeri... | lld:pubmed |
| pubmed-article:16933259 | pubmed:author | pubmed-author:BaronciCarloC | lld:pubmed |
| pubmed-article:16933259 | pubmed:author | pubmed-author:ColettiValent... | lld:pubmed |
| pubmed-article:16933259 | pubmed:author | pubmed-author:FunaroDariaD | lld:pubmed |
| pubmed-article:16933259 | pubmed:copyrightInfo | Copyright (c) 2006 Wiley-Liss, Inc. | lld:pubmed |
| pubmed-article:16933259 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16933259 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:16933259 | pubmed:volume | 47 | lld:pubmed |
| pubmed-article:16933259 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16933259 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16933259 | pubmed:pagination | 665-7 | lld:pubmed |
| pubmed-article:16933259 | pubmed:dateRevised | 2009-1-12 | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:meshHeading | pubmed-meshheading:16933259... | lld:pubmed |
| pubmed-article:16933259 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16933259 | pubmed:articleTitle | Idiopathic thrombocytopenic purpura (ITP) in children. | lld:pubmed |
| pubmed-article:16933259 | pubmed:affiliation | Hematology Division, Children's Hospital Bambino Gesù, Rome, Vatican City, Italy. | lld:pubmed |
| pubmed-article:16933259 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16933259 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:16933259 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
