pubmed-article:16893518 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C0769345 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C0015295 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C0679058 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C1547699 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C2700640 | lld:lifeskim |
pubmed-article:16893518 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:16893518 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:16893518 | pubmed:dateCreated | 2006-8-14 | lld:pubmed |
pubmed-article:16893518 | pubmed:abstractText | Caspase-5 is a caspase-1-like protease with pro-apoptotic and pro-inflammatory activities. Here we have identified a novel exon at the 5'-end of the human caspase-5 gene. This novel exon was present in six alternatively spliced caspase-5 mRNA variants expressed in human peripheral blood mononuclear cells (PBMC) and encoded the previously unknown amino-terminus of caspase-5. The genomic region upstream of this exon contained sequence elements homologous to those of the caspase-11 promoter in the mouse, and transcription of caspase-5 was upregulated by lipopolysaccharide (LPS) in a caspase-11-like manner in human PBMC in vivo. Taken together, our findings call for a revision of the structure of caspase-5 at the genomic level as well as at the mRNA and protein levels. | lld:pubmed |
pubmed-article:16893518 | pubmed:language | eng | lld:pubmed |
pubmed-article:16893518 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16893518 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16893518 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16893518 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16893518 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16893518 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16893518 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16893518 | pubmed:month | Sep | lld:pubmed |
pubmed-article:16893518 | pubmed:issn | 0006-291X | lld:pubmed |
pubmed-article:16893518 | pubmed:author | pubmed-author:MildnerMichae... | lld:pubmed |
pubmed-article:16893518 | pubmed:author | pubmed-author:EckhartLeopol... | lld:pubmed |
pubmed-article:16893518 | pubmed:author | pubmed-author:TschachlerErw... | lld:pubmed |
pubmed-article:16893518 | pubmed:author | pubmed-author:GruberFlorian... | lld:pubmed |
pubmed-article:16893518 | pubmed:author | pubmed-author:JilmaBerndB | lld:pubmed |
pubmed-article:16893518 | pubmed:author | pubmed-author:KittelChristi... | lld:pubmed |
pubmed-article:16893518 | pubmed:author | pubmed-author:GawlasSonjaS | lld:pubmed |
pubmed-article:16893518 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16893518 | pubmed:day | 22 | lld:pubmed |
pubmed-article:16893518 | pubmed:volume | 348 | lld:pubmed |
pubmed-article:16893518 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16893518 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16893518 | pubmed:pagination | 682-8 | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:meshHeading | pubmed-meshheading:16893518... | lld:pubmed |
pubmed-article:16893518 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16893518 | pubmed:articleTitle | Identification of a novel exon encoding the amino-terminus of the predominant caspase-5 variants. | lld:pubmed |
pubmed-article:16893518 | pubmed:affiliation | Department of Dermatology, Medical University of Vienna, A-1090 Vienna, Austria. | lld:pubmed |
pubmed-article:16893518 | pubmed:publicationType | Journal Article | lld:pubmed |
entrez-gene:838 | entrezgene:pubmed | pubmed-article:16893518 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:16893518 | lld:entrezgene |