| pubmed-article:16870427 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C0065898 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C0019927 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C0034424 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C0376607 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:16870427 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:16870427 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:16870427 | pubmed:dateCreated | 2006-8-25 | lld:pubmed |
| pubmed-article:16870427 | pubmed:abstractText | A novel series of substituted quinoline analogs were designed and synthesized as potent and selective melanin concentrating hormone (MCH) antagonists. These analogs show potent (nM) activity (12a-k) with a moderate selectivity. Conversely, the conformationally constrained thienopyrimidinone analogs (18a-g) showed improved activity in MCH-1R and selectivity over 5HT2C. | lld:pubmed |
| pubmed-article:16870427 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16870427 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16870427 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:16870427 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16870427 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:16870427 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:16870427 | pubmed:author | pubmed-author:YaeYY | lld:pubmed |
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| pubmed-article:16870427 | pubmed:author | pubmed-author:ReizesOferO | lld:pubmed |
| pubmed-article:16870427 | pubmed:author | pubmed-author:WarshakoonNam... | lld:pubmed |
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| pubmed-article:16870427 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16870427 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:16870427 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:16870427 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16870427 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16870427 | pubmed:pagination | 5207-11 | lld:pubmed |
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| pubmed-article:16870427 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16870427 | pubmed:articleTitle | Design and synthesis of substituted quinolines as novel and selective melanin concentrating hormone antagonists as anti-obesity agents. | lld:pubmed |
| pubmed-article:16870427 | pubmed:affiliation | Drug Discovery Division, Procter and Gamble Pharmaceuticals Inc., 8700 Mason-Montgomery Road, Mason, OH 45040, USA. Warshakoon.nc@pg.com | lld:pubmed |
| pubmed-article:16870427 | pubmed:publicationType | Journal Article | lld:pubmed |
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