Linked Life Data

16864166

Source:http://linkedlifedata.com/resource/pubmed/id/16864166

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:16864166rdf:typepubmed:Citationlld:pubmed
pubmed-article:16864166lifeskim:mentionsumls-concept:C0024671lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C0032659lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C0008976lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C1522449lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C0007124lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C0006141lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C0220908lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C0728940lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C1274040lld:lifeskim
pubmed-article:16864166lifeskim:mentionsumls-concept:C1708237lld:lifeskim
pubmed-article:16864166pubmed:issue5lld:pubmed
pubmed-article:16864166pubmed:dateCreated2006-7-25lld:pubmed
pubmed-article:16864166pubmed:abstractTextWe studied the effect of postoperative radiotherapy (RT) after breast sector resection for ductal carcinoma in situ (DCIS). The study protocol stipulated radical surgery but microscopically clear margins were not mandatory. We randomised 1,046 operated women to postoperative RT or control between 1987 and 1999. The primary endpoint was ipsilateral local recurrence. Secondary endpoints were contralateral breast cancer, distant metastasis and death. After a median follow-up of 5.2 years (range 0.1-13.8) there were 44 recurrences in the RT group corresponding to a cumulative incidence of 0.07 (95% confidence interval (CI) 0.05-0.10). In the control group there were 117 recurrences giving a cumulative incidence of 0.22 (95% CI 0.18-0.26) giving an overall hazard ratio of 0.33 (95% CI 0.24-0.47, p < 0.0001). Twenty two percent of the patients had microscopically unknown or involved margins. We found no evidence for different effects of RT on the relative risk of invasive or in situ recurrence. Secondary endpoints did not differ. Women undergoing sector resection for DCIS under conditions of population based screening mammography benefit from postoperative RT to the breast. Seven patients needed RT-treatment to prevent one recurrence.lld:pubmed
pubmed-article:16864166pubmed:languageenglld:pubmed
pubmed-article:16864166pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16864166pubmed:citationSubsetIMlld:pubmed
pubmed-article:16864166pubmed:statusMEDLINElld:pubmed
pubmed-article:16864166pubmed:issn0284-186Xlld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:HolmbergLarsLlld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:RingbergAnita...lld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:EmdinStefan...lld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:WallgrenArneAlld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:AndersonHaral...lld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:SandelinKerst...lld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:NordgrenHansHlld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:GarmoHansHlld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:Swedish...lld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:GranstrandBen...lld:pubmed
pubmed-article:16864166pubmed:authorpubmed-author:ArnessonLars-...lld:pubmed
pubmed-article:16864166pubmed:issnTypePrintlld:pubmed
pubmed-article:16864166pubmed:volume45lld:pubmed
pubmed-article:16864166pubmed:ownerNLMlld:pubmed
pubmed-article:16864166pubmed:authorsCompleteYlld:pubmed
pubmed-article:16864166pubmed:pagination536-43lld:pubmed
pubmed-article:16864166pubmed:dateRevised2009-5-12lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:meshHeadingpubmed-meshheading:16864166...lld:pubmed
pubmed-article:16864166pubmed:year2006lld:pubmed
pubmed-article:16864166pubmed:articleTitleSweDCIS: Radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening.lld:pubmed
pubmed-article:16864166pubmed:affiliationDepartment of Surgery, Umeå University Hospital, Umeå, Sweden. stefan.emdin@surgery.umu.selld:pubmed
pubmed-article:16864166pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16864166pubmed:publicationTypeRandomized Controlled Triallld:pubmed
pubmed-article:16864166pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16864166lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16864166lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16864166lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16864166lld:pubmed