| pubmed-article:1685644 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0002395 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0030664 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0027895 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0725066 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0332185 | lld:lifeskim |
| pubmed-article:1685644 | lifeskim:mentions | umls-concept:C0599668 | lld:lifeskim |
| pubmed-article:1685644 | pubmed:dateCreated | 1992-2-28 | lld:pubmed |
| pubmed-article:1685644 | pubmed:abstractText | Our findings from three postmortem tissue studies in Alzheimer's disease (AD) are presented. We investigated (1) alterations in somatostatin (SRIF) and corticotropin-releasing factor (CRF) in AD; (2) regulatory changes in presynaptic cholinergic function in AD; and (3) use of Alzheimer's disease-associated protein (ADAP) as a diagnostic test for AD in postmortem tissue. Taken together, these findings reveal marked reductions in SRIF and CRF concentrations in many cerebrocortical areas in AD, a marked up-regulation of cholinergic neuronal activity in surviving cholinergic neurons in AD, and excellent specificity and sensitivity for the use of the ADAP assay as a diagnostic test for AD in postmortem tissue. | lld:pubmed |
| pubmed-article:1685644 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685644 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685644 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1685644 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685644 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1685644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685644 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1685644 | pubmed:issn | 0077-8923 | lld:pubmed |
| pubmed-article:1685644 | pubmed:author | pubmed-author:SlotkinT ATA | lld:pubmed |
| pubmed-article:1685644 | pubmed:author | pubmed-author:SeidlerF JFJ | lld:pubmed |
| pubmed-article:1685644 | pubmed:author | pubmed-author:GhanbariHH | lld:pubmed |
| pubmed-article:1685644 | pubmed:author | pubmed-author:BissetteGG | lld:pubmed |
| pubmed-article:1685644 | pubmed:author | pubmed-author:NemeroffC BCB | lld:pubmed |
| pubmed-article:1685644 | pubmed:author | pubmed-author:MillerB EBE | lld:pubmed |
| pubmed-article:1685644 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1685644 | pubmed:volume | 640 | lld:pubmed |
| pubmed-article:1685644 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1685644 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1685644 | pubmed:pagination | 193-6 | lld:pubmed |
| pubmed-article:1685644 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:1685644 | pubmed:meshHeading | pubmed-meshheading:1685644-... | lld:pubmed |
| pubmed-article:1685644 | pubmed:meshHeading | pubmed-meshheading:1685644-... | lld:pubmed |
| pubmed-article:1685644 | pubmed:meshHeading | pubmed-meshheading:1685644-... | lld:pubmed |
| pubmed-article:1685644 | pubmed:meshHeading | pubmed-meshheading:1685644-... | lld:pubmed |
| pubmed-article:1685644 | pubmed:meshHeading | pubmed-meshheading:1685644-... | lld:pubmed |
| pubmed-article:1685644 | pubmed:meshHeading | pubmed-meshheading:1685644-... | lld:pubmed |
| pubmed-article:1685644 | pubmed:meshHeading | pubmed-meshheading:1685644-... | lld:pubmed |
| pubmed-article:1685644 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1685644 | pubmed:articleTitle | Recent advances in the neurochemical pathology of Alzheimer's disease. Studies of neuropeptides, cholinergic function and Alzheimer's disease-associated protein. | lld:pubmed |
| pubmed-article:1685644 | pubmed:affiliation | Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710. | lld:pubmed |
| pubmed-article:1685644 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1685644 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1685644 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1685644 | lld:pubmed |
