| pubmed-article:1685129 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C0011849 | lld:lifeskim |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C1420172 | lld:lifeskim |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C0796344 | lld:lifeskim |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C0035268 | lld:lifeskim |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C0439064 | lld:lifeskim |
| pubmed-article:1685129 | lifeskim:mentions | umls-concept:C0018591 | lld:lifeskim |
| pubmed-article:1685129 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:1685129 | pubmed:dateCreated | 1992-2-24 | lld:pubmed |
| pubmed-article:1685129 | pubmed:abstractText | The liver/islet glucose transporter (GLUT2) is expressed in the liver and in the Beta cells of pancreatic islets and is a candidate gene for the inherited defect in Type 2 (non-insulin-dependent) diabetes mellitus. A series of restriction fragment length polymorphisms have been identified using a GLUT2 cDNA probe with five restriction enzymes in a British white Caucasian population. Five independent restriction fragment length polymorphisms detected by restriction enzymes EcoRI (two restriction fragment length polymorphisms termed EcoRI-1, EcoRI-2), TaqI (two restriction fragment length polymorphisms termed TaqI-1, TaqI-2), and BclI (BclI-2) were used to construct GLUT2 haplotypes. Significant linkage disequilibrium was observed between four polymorphic sites EcoRI-2, TaqI-1, TaqI-2 and BclI-2 but linkage disequilibrium was not observed with EcoRI-1 polymorphic site and the other four sites. The frequencies of GLUT2 restriction fragment length polymorphisms and haplotypes in 50 Type 2 diabetic subjects and 50 non-diabetic control subjects show no significant differences suggesting that it is unlikely that there is a single major defect of this gene contributing to the inherited susceptibility to Type 2 diabetes in a Caucasian population. | lld:pubmed |
| pubmed-article:1685129 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1685129 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1685129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1685129 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1685129 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1685129 | pubmed:issn | 0012-186X | lld:pubmed |
| pubmed-article:1685129 | pubmed:author | pubmed-author:PaterJJ | lld:pubmed |
| pubmed-article:1685129 | pubmed:author | pubmed-author:WainscoatJ... | lld:pubmed |
| pubmed-article:1685129 | pubmed:author | pubmed-author:COLEL JLJ | lld:pubmed |
| pubmed-article:1685129 | pubmed:author | pubmed-author:TurnerR CRC | lld:pubmed |
| pubmed-article:1685129 | pubmed:author | pubmed-author:CookJ TJT | lld:pubmed |
| pubmed-article:1685129 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1685129 | pubmed:volume | 34 | lld:pubmed |
| pubmed-article:1685129 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1685129 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1685129 | pubmed:pagination | 817-21 | lld:pubmed |
| pubmed-article:1685129 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:meshHeading | pubmed-meshheading:1685129-... | lld:pubmed |
| pubmed-article:1685129 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1685129 | pubmed:articleTitle | Multiple restriction fragment length polymorphisms at the GLUT2 locus: GLUT2 haplotypes for genetic analysis of type 2 (non-insulin-dependent) diabetes mellitus. | lld:pubmed |
| pubmed-article:1685129 | pubmed:affiliation | Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Headington, Oxford, UK. | lld:pubmed |
| pubmed-article:1685129 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1685129 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1685129 | lld:pubmed |
