| pubmed-article:16843877 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C0015733 | lld:lifeskim |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C0020885 | lld:lifeskim |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C0400076 | lld:lifeskim |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C0439810 | lld:lifeskim |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C1159690 | lld:lifeskim |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C0442540 | lld:lifeskim |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:16843877 | lifeskim:mentions | umls-concept:C0205224 | lld:lifeskim |
| pubmed-article:16843877 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:16843877 | pubmed:dateCreated | 2006-7-17 | lld:pubmed |
| pubmed-article:16843877 | pubmed:abstractText | Our previous studies demonstrated that sodium glucose cotransporter 1 (SGLT-1) was induced in the remnant ileum of total colectomized rats via the action of factors other than hyperaldosteronism. The aim of the present study was to clarify whether fecal stream is required for the enhancement of SGLT-1-mediated sodium transport. Twenty-seven pairs of ileal tissues were obtained from the proximal and distal side, respectively, of loop ileostomy after total proctocolectomy. Mucosae were mounted in an Ussing chamber to evaluate glucose-coupled sodium transport. Levels of SGLT-1 mRNA in proximal and distal mucosae were compared by Northern blotting. Villous height and crypt depth were measured to test for correlations between mucosal structure and SGLT-1-mediated sodium transport or mRNA expression levels. Both glucose-coupled sodium transport and expression of SGLT-1 mRNA were significantly lower in distal mucosae relative to proximal mucosae. In distal mucosae, villous height, but not crypt depth, was significantly lower than in proximal mucosae, demonstrating a positive correlation between villous height and SGLT-1 function and expression. Comparative studies of proximal and distal mucosae demonstrated that in addition to hormonal changes, fecal stream is required for full induction of the sodium transport system (which includes SGLT-1-mediated transport) in the remnant ileum following total proctocolectomy. | lld:pubmed |
| pubmed-article:16843877 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16843877 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16843877 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16843877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16843877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16843877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16843877 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16843877 | pubmed:issn | 1091-255X | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:ShibataChikas... | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:FunayamaYujiY | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:FukushimaKouh... | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:SasakiIwaoI | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:WatanabeKazuh... | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:OgawaHitoshiH | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:NagaoMunenori... | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:TakahashiKen-... | lld:pubmed |
| pubmed-article:16843877 | pubmed:author | pubmed-author:HanedaShoS | lld:pubmed |
| pubmed-article:16843877 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16843877 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:16843877 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16843877 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16843877 | pubmed:pagination | 1051-9 | lld:pubmed |
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| pubmed-article:16843877 | pubmed:articleTitle | Fecal stream is essential for adaptive induction of glucose-coupled sodium transport in the remnant ileum after total proctocolectomy. | lld:pubmed |
| pubmed-article:16843877 | pubmed:affiliation | Department of Surgery, Tohoku University, Graduate School of Medicine, Sendai, Japan. | lld:pubmed |
| pubmed-article:16843877 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16843877 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16843877 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:16843877 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
