| pubmed-article:16808644 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16808644 | lifeskim:mentions | umls-concept:C0032961 | lld:lifeskim |
| pubmed-article:16808644 | lifeskim:mentions | umls-concept:C0041633 | lld:lifeskim |
| pubmed-article:16808644 | lifeskim:mentions | umls-concept:C0015927 | lld:lifeskim |
| pubmed-article:16808644 | lifeskim:mentions | umls-concept:C0032980 | lld:lifeskim |
| pubmed-article:16808644 | lifeskim:mentions | umls-concept:C0332528 | lld:lifeskim |
| pubmed-article:16808644 | lifeskim:mentions | umls-concept:C1524003 | lld:lifeskim |
| pubmed-article:16808644 | lifeskim:mentions | umls-concept:C0522498 | lld:lifeskim |
| pubmed-article:16808644 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16808644 | pubmed:dateCreated | 2006-6-30 | lld:pubmed |
| pubmed-article:16808644 | pubmed:abstractText | Little attention has been paid to the pathologic features of the umbilical cord, which might fatally damage the fetus. We determined the association of hypercoiling (more than 1 coil per 5 cm) and thinning with consecutive constriction of the umbilical vessels (thin cord syndrome; TCS) and intrauterine fetal death (IUFD). Three hundred and three cases of consecutive fetal autopsies over a 5-year period, including spontaneous and induced abortions of the 2nd trimester of pregnancy, were examined using a standardized protocol. The mean maternal age was 28.5 years and the mean gestational age was 19.1 weeks (range: 12.6 to 24.5 weeks). Thirty-six percent of all cases were induced abortions because of congenital malformations, and 8.9% resulted from legal abortions, as regulated by German law. One hundred sixty-seven cases (55.1%) were spontaneous abortion specimens. The leading cause for IUFD in the spontaneous abortion group was an amnion infection (34.7%), followed by abruptio placentae (15.6%). In 25.1% of cases, placental dysmaturity with consecutive placental insufficiency was responsible for IUFD. Pathologies of the umbilical cord as the cause of IUFD were seen in 10.2% of the cases. Most of these cases (15/17) involved TCS. In 14.4% of all spontaneous abortion specimens the cause of IUFD could not be determined by autopsy. There was an apparent difference in the frequency of TCS in the spontaneous abortion group (15/167 = 9%) compared to the nonspontaneous group (2/136 = 1.5%). A remarkably high percentage (17/303 = 5.6%) of all cases showed TCS. In cases of spontaneous abortions, TCS was causative for intrauterine death in 9% of cases (15/167). Careful pathologic examination of the umbilical cord is recommended to detect TCS and to reduce the cases with unexplained intrauterine death. | lld:pubmed |
| pubmed-article:16808644 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16808644 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16808644 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16808644 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16808644 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16808644 | pubmed:issn | 1093-5266 | lld:pubmed |
| pubmed-article:16808644 | pubmed:author | pubmed-author:WittekindChri... | lld:pubmed |
| pubmed-article:16808644 | pubmed:author | pubmed-author:HornLars-Chri... | lld:pubmed |
| pubmed-article:16808644 | pubmed:author | pubmed-author:StepanHolgerH | lld:pubmed |
| pubmed-article:16808644 | pubmed:author | pubmed-author:FaberRenaldoR | lld:pubmed |
| pubmed-article:16808644 | pubmed:author | pubmed-author:SimonEikeE | lld:pubmed |
| pubmed-article:16808644 | pubmed:author | pubmed-author:RobelRalfR | lld:pubmed |
| pubmed-article:16808644 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16808644 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:16808644 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16808644 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16808644 | pubmed:pagination | 20-4 | lld:pubmed |
| pubmed-article:16808644 | pubmed:dateRevised | 2007-5-4 | lld:pubmed |
| pubmed-article:16808644 | pubmed:meshHeading | pubmed-meshheading:16808644... | lld:pubmed |
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| pubmed-article:16808644 | pubmed:meshHeading | pubmed-meshheading:16808644... | lld:pubmed |
| pubmed-article:16808644 | pubmed:articleTitle | Umbilical cord hypercoiling and thinning: a rare cause of intrauterine death in the second trimester of pregnancy. | lld:pubmed |
| pubmed-article:16808644 | pubmed:affiliation | Institute of Pathology, University Hospital of Leipzig, Leipzig, Germany. hornl@medizin.uni-leipzig.de | lld:pubmed |
| pubmed-article:16808644 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16808644 | lld:pubmed |
