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pubmed-article:16796750pubmed:abstractTextActivation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to chemotherapy shown in this type of tumor. The aim of the present study was to investigate the mechanism of caspase-9 inhibition, with a focus on a possible role of TUCAN as caspase-9 inhibitor and a determinant of chemosensitivity in NSCLC cells.lld:pubmed
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pubmed-article:16796750pubmed:articleTitleTUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells.lld:pubmed
pubmed-article:16796750pubmed:affiliationDepartment of Medical Oncology, VU University Medical Center, 1081 HV Amsterdam, The Netherlands. a.checinska@vumc.nllld:pubmed
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