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pubmed-article:16770770pubmed:abstractTextIt has been previously observed that patients with head and neck squamous cell carcinoma or with laryngeal leucoplakia present a significant reduction in plasma folate levels. The current Phase IIA pilot study assessed the effectiveness of folic acid as a chemopreventive agent in patients affected by glottic laryngeal leucoplakia.lld:pubmed
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pubmed-article:16770770pubmed:articleTitlePilot phase IIA study for evaluation of the efficacy of folic acid in the treatment of laryngeal leucoplakia.lld:pubmed
pubmed-article:16770770pubmed:affiliationInstitute of Otolaryngology, Universita Cattolica del Sacro Cuore, Policlinico A. Gemelli, Rome, Italy. almgio@yahoo.itlld:pubmed
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