pubmed-article:1676875 | pubmed:abstractText | Flupirtine is a new non-opioid, non-addicting centrally acting analgesic. In animals, antinociceptive activity of flupirtine was attenuated after reserpine pretreatment or in the presence of alpha-adrenergic antagonists suggesting the possible involvement of the noradrenergic system in its analgesic mode of action. Additionally, flupirtine possesses skeletal muscle relaxing activity in rats. | lld:pubmed |