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pubmed-article:1676875pubmed:abstractTextFlupirtine is a new non-opioid, non-addicting centrally acting analgesic. In animals, antinociceptive activity of flupirtine was attenuated after reserpine pretreatment or in the presence of alpha-adrenergic antagonists suggesting the possible involvement of the noradrenergic system in its analgesic mode of action. Additionally, flupirtine possesses skeletal muscle relaxing activity in rats.lld:pubmed
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pubmed-article:1676875pubmed:articleTitlePharmacological profile of flupirtine, a novel centrally acting, non-opioid analgesic drug.lld:pubmed
pubmed-article:1676875pubmed:affiliationDepartment of Pharmacology, ASTA Pharma AG, Frankfurt/M., FRG.lld:pubmed
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