A new oleanane-type triterpenoid (1) and five known pentacyclic triterpenoids (2-6) were isolated from the leaves of Excoecaria agallocha. Their structures were elucidated by spectroscopic analyses. The new compound was characterized as 3beta-[(2E,4E)-5-oxo-decadienoyloxy]-olean-12-ene (1). Compounds 1-6 were found inactive in vitro against several human cancer cell lines.
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education, Beijing 100050, PR China.
