| pubmed-article:1675317 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1675317 | lifeskim:mentions | umls-concept:C0020094 | lld:lifeskim |
| pubmed-article:1675317 | lifeskim:mentions | umls-concept:C0005795 | lld:lifeskim |
| pubmed-article:1675317 | lifeskim:mentions | umls-concept:C0035648 | lld:lifeskim |
| pubmed-article:1675317 | lifeskim:mentions | umls-concept:C0020102 | lld:lifeskim |
| pubmed-article:1675317 | lifeskim:mentions | umls-concept:C0033105 | lld:lifeskim |
| pubmed-article:1675317 | lifeskim:mentions | umls-concept:C0205345 | lld:lifeskim |
| pubmed-article:1675317 | pubmed:issue | 8755 | lld:pubmed |
| pubmed-article:1675317 | pubmed:dateCreated | 1991-7-17 | lld:pubmed |
| pubmed-article:1675317 | pubmed:abstractText | The clinical significance of human T-cell lymphotropic virus type II (HTLV-II) infection, unlike that of HTLV-I, is unknown, and the major known association of HTLV-II seropositivity is with intravenous drug abuse. Screening of blood donors for HTLV-I, now routine in North America, does not distinguish this retrovirus from HTLV-II. To find out more about the seroepidemiology of and risk factors for HTLV I and II, blood from 480,000 volunteer donors in five geographically separate US urban centres was tested for antibodies to HTLV-I/II and HIV-1. Confirmed HTLV-I/II seropositive donors were then followed up by DNA amplification to distinguish type I from type II and by interviews focusing on possible risk factors. HTLV seroprevalence was 3.3 times greater than that for HIV-1 (0.043% vs 0.013%). DNA amplification on 65 of the 207 HTLV-I/II seropositive donors revealed that 34 (52%) had HTLV-II infection and 28 (43% had HTLV-I; 3 samples were uninformative. Interviews of 49 donors showed that whereas HTLV-I was principally associated with donor origin from endemic regions, the major risk factor for HTLV-II infection was intravenous drug use. The surprisingly high rate of HTLV-II infection in US blood donors raises important public health and donor counselling issues since HTLV-I infection is associated with adult T-cell leukaemia and a neurological disorder while the pathogenicity of HTLV-II is as yet unclear. | lld:pubmed |
| pubmed-article:1675317 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1675317 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1675317 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:1675317 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1675317 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1675317 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:1675317 | pubmed:issn | 0140-6736 | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:FernandoL PLP | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:OsameMM | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:SmithD EDE | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:TegtmeierG... | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:SherwoodW CWC | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:LeeH HHH | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:SwansonPP | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:FangC TCT | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:ChenI SIS | lld:pubmed |
| pubmed-article:1675317 | pubmed:author | pubmed-author:RosenblattJ... | lld:pubmed |
| pubmed-article:1675317 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1675317 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:1675317 | pubmed:volume | 337 | lld:pubmed |
| pubmed-article:1675317 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1675317 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:1675317 | pubmed:pagination | 1435-9 | lld:pubmed |
| pubmed-article:1675317 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1675317 | pubmed:meshHeading | pubmed-meshheading:1675317-... | lld:pubmed |
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| pubmed-article:1675317 | pubmed:meshHeading | pubmed-meshheading:1675317-... | lld:pubmed |
| pubmed-article:1675317 | pubmed:meshHeading | pubmed-meshheading:1675317-... | lld:pubmed |
| pubmed-article:1675317 | pubmed:meshHeading | pubmed-meshheading:1675317-... | lld:pubmed |
| pubmed-article:1675317 | pubmed:meshHeading | pubmed-meshheading:1675317-... | lld:pubmed |
| pubmed-article:1675317 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1675317 | pubmed:articleTitle | Relative prevalence and risk factors of HTLV-I and HTLV-II infection in US blood donors. | lld:pubmed |
| pubmed-article:1675317 | pubmed:affiliation | Abbott Laboratories Diagnostic Division, North Chicago, IL 60064. | lld:pubmed |
| pubmed-article:1675317 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1675317 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1675317 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1675317 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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