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pubmed-article:16753018pubmed:abstractTextThe bone phenotype of mice overexpressing MIF was studied. These mice showed decreased trabecular bone, increased bone formation rate, and increased MMP-3, -9, and -13 mRNA expression in the femora and tibias. This model provides evidence of the role played by MIF in bone remodeling and balance in vivo.lld:pubmed
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pubmed-article:16753018pubmed:articleTitleTransgenic mice overexpressing macrophage migration inhibitory factor (MIF) exhibit high-turnover osteoporosis.lld:pubmed
pubmed-article:16753018pubmed:affiliationDepartment of Sports Medicine and Joint Recontruction Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan. onodera@med.hokuda.ac.jplld:pubmed
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