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pubmed-article:16735938pubmed:abstractTextEstrogen therapy (ET) seems to differentially effect cognitive processes in younger versus older postmenopausal women, suggesting a window of opportunity when ET is most beneficial. Cognitive improvement in younger postmenopausal women has been attributed to ET's influence on hot flushes and sleep, but empiric examination of the mediating role of menopause symptoms versus direct effects of ET on the brain is limited.lld:pubmed
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pubmed-article:16735938pubmed:articleTitleEstrogen therapy selectively enhances prefrontal cognitive processes: a randomized, double-blind, placebo-controlled study with functional magnetic resonance imaging in perimenopausal and recently postmenopausal women.lld:pubmed
pubmed-article:16735938pubmed:affiliationWomen's Center for Behavioral Endocrinology, McLean Hospital, Harvard Medical School, Boston, MA, USA. hjoffe@partners.orglld:pubmed
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