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pubmed-article:16718274pubmed:abstractTextExperimental and clinical evidence indicates that non-steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors may have anti-cancer activities. Here we report on a patient with a metastatic melanoma of the leg who experienced a complete and sustained regression of skin metastases upon continuous single treatment with the cyclooxygenase-2 inhibitor rofecoxib. Our observations indicate that the inhibition of cyclooxygenase-2 can lead to the regression of disseminated skin melanoma metastases, even after failure of chemotherapy.lld:pubmed
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pubmed-article:16718274pubmed:articleTitleComplete and long-lasting regression of disseminated multiple skin melanoma metastases under treatment with cyclooxygenase-2 inhibitor.lld:pubmed
pubmed-article:16718274pubmed:affiliationDepartment of Visceral Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne Switzerland. Ferdy.Lejeune@chuv.chlld:pubmed
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