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pubmed-article:16717212pubmed:abstractTextInterpretation of treatment trials in vascular dementia is confounded by the presence of coexistent Alzheimer disease (AD) pathology. The younger onset genetic disease cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) offers a model of pure vascular dementia, in which such confounding is unlikely. To validate CADASIL's use as a model it is important to show it results in a similar cognitive impairment.lld:pubmed
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pubmed-article:16717212pubmed:year2006lld:pubmed
pubmed-article:16717212pubmed:articleTitleThe cognitive profiles of CADASIL and sporadic small vessel disease.lld:pubmed
pubmed-article:16717212pubmed:affiliationClinical Neuroscience, St. George's University of London, UK.lld:pubmed
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