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pubmed-article:16714600pubmed:abstractTextInterstitial lung macrophages from tuberculosis-susceptible I/St and tuberculosis-resistant A/Sn mice demonstrated significant constitutive differences in gene expression levels, whereas in vitro infection of these cells with Mycobacterium tuberculosis had only a modulatory impact on gene expression. We conclude that intrinsic gene expression profiles are an important determinant of tuberculosis pathogenesis in mice.lld:pubmed
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pubmed-article:16714600pubmed:articleTitleConstitutive differences in gene expression profiles parallel genetic patterns of susceptibility to tuberculosis in mice.lld:pubmed
pubmed-article:16714600pubmed:affiliationLaboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia. asapt@aha.ru.lld:pubmed
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