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pubmed-article:16708128pubmed:abstractTextA chemical worker working with urea-formaldehyde resin hazard for 20 years suffered cerebral ischemia in association with an increase of blood beta2-glycoprotein I-dependent anticardiolipin antibody (aCL)-IgG and IgM isotype, and a prolongation of activated partial thromboplastin time (aPTT). Major histocompatibility complex antigen showed DR4 positivity. On follow-up for over 6 years, aCL-IgG and aPTT decreased to reference range but aCL-IgM was still abnormally high despite a cessation of exposure. This patient highlights the induction of antibody-mediated thrombosis in chronic chemical exposure, especially in an individual with subclinical autoimmune disorder. The role of environment for coagulopathic vascular thrombosis is warranted for investigation.lld:pubmed
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pubmed-article:16708128pubmed:authorpubmed-author:LuiChun-Chung...lld:pubmed
pubmed-article:16708128pubmed:authorpubmed-author:ChenChung-Jen...lld:pubmed
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pubmed-article:16708128pubmed:authorpubmed-author:LiuJia-ShouJSlld:pubmed
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pubmed-article:16708128pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:16708128pubmed:articleTitleAn increase of anticardiolipin antibody in association with stroke and chronic chemical exposure.lld:pubmed
pubmed-article:16708128pubmed:affiliationStroke Biology Research Laboratory, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.lld:pubmed
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