Analysis of fibrinogen variants at gamma387Ile shows that the side chain of gamma387 and the tertiary structure of the gammaC-terminal tail are important not only for assembly and secretion of fibrinogen but also for lateral aggregation of protofibrils and XIIIa-catalyzed gamma-gamma dimer formation.
Source:http://linkedlifedata.com/resource/pubmed/id/16705085
Blood
2006
Sep
15
108
6
1887-94
