Linked Life Data

16697745

Source:http://linkedlifedata.com/resource/pubmed/id/16697745

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pubmed-article:16697745pubmed:abstractTextThere is poor knowledge on the factors that modulate the growth of cholangiocytes, the epithelial cell target of cholangiopathies, which are diseases leading to progressive loss of bile ducts and liver failure. Endogenous opioids are known to modulate cell growth. In the course of cholestasis, the opioidergic system is hyperactive, and in cholangiocytes a higher expression of opioid peptide messenger RNA has been described. This study aimed to verify if such events affect the cholangiocyte proliferative response to cholestasis.lld:pubmed
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pubmed-article:16697745pubmed:articleTitleEndogenous opioids modulate the growth of the biliary tree in the course of cholestasis.lld:pubmed
pubmed-article:16697745pubmed:affiliationDepartment of Gastroenterology, Università Politecnica delle Marche, Ancona, Italy. marco.marzioni@tele2.itlld:pubmed
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