Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:16661830rdf:typepubmed:Citationlld:pubmed
pubmed-article:16661830lifeskim:mentionsumls-concept:C0007634lld:lifeskim
pubmed-article:16661830lifeskim:mentionsumls-concept:C0242437lld:lifeskim
pubmed-article:16661830lifeskim:mentionsumls-concept:C0007341lld:lifeskim
pubmed-article:16661830lifeskim:mentionsumls-concept:C0204727lld:lifeskim
pubmed-article:16661830lifeskim:mentionsumls-concept:C0205409lld:lifeskim
pubmed-article:16661830lifeskim:mentionsumls-concept:C1999216lld:lifeskim
pubmed-article:16661830lifeskim:mentionsumls-concept:C1515100lld:lifeskim
pubmed-article:16661830lifeskim:mentionsumls-concept:C0064257lld:lifeskim
pubmed-article:16661830pubmed:issue6lld:pubmed
pubmed-article:16661830pubmed:dateCreated2010-6-29lld:pubmed
pubmed-article:16661830pubmed:abstractTextBiosynthesis of ent-kaurene was investigated in extracts of cell suspension cultures and seedlings of castor bean. Both cell-free extracts contain an inhibitor of kaurene synthetase. The inhibition affects mainly the cyclization of geranylgeranyl pyrophosphate to copalyl pyrophosphate (activity A) and has little or no effect on the further cyclization of copalyl pyrophosphate to ent-kaurene (activity B) in both castor bean and Fusarium moniliforme cell-free enzyme preparations. In castor bean cell suspension cultures, the inhibitor diffuses out of the cells to the growth medium. The inhibitor is stable to 100 C heat treatment for 10 minutes and exposure to pH values of 2.0 or 13.0, and it diffuses through a dialysis bag (10(4)-dalton cutoff). Gel filtration chromatography of the inhibitor on a calibrated Bio-Gel P-10 column indicated a molecular weight of 7,500. Kinetic studies indicate that the inhibition of activity of A of kaurene synthetase is noncompetitive and reversible.lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:languageenglld:pubmed
pubmed-article:16661830pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:16661830pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:16661830pubmed:monthJunlld:pubmed
pubmed-article:16661830pubmed:issn0032-0889lld:pubmed
pubmed-article:16661830pubmed:authorpubmed-author:GafniYYlld:pubmed
pubmed-article:16661830pubmed:authorpubmed-author:ShechterIIlld:pubmed
pubmed-article:16661830pubmed:issnTypePrintlld:pubmed
pubmed-article:16661830pubmed:volume67lld:pubmed
pubmed-article:16661830pubmed:ownerNLMlld:pubmed
pubmed-article:16661830pubmed:authorsCompleteYlld:pubmed
pubmed-article:16661830pubmed:pagination1169-73lld:pubmed
pubmed-article:16661830pubmed:dateRevised2010-9-15lld:pubmed
pubmed-article:16661830pubmed:year1981lld:pubmed
pubmed-article:16661830pubmed:articleTitleIsolation of a kaurene synthetase inhibitor from castor bean seedlings and cell suspension cultures.lld:pubmed
pubmed-article:16661830pubmed:affiliationDepartment of Biochemistry, The George S. Wise Center for Life Sciences, Tel-Aviv University, Ramat-Aviv, Tel-Aviv, Israel.lld:pubmed
pubmed-article:16661830pubmed:publicationTypeJournal Articlelld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16661830lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:16661830lld:pubmed