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pubmed-article:16650762pubmed:abstractTextA series of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives were synthesized as motilin receptor antagonists. Starting from known motilin antagonists, 1a and 1b, the cyclopentene scaffold was replaced and the four recognition elements optimized to arrive at a potent novel series.lld:pubmed
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pubmed-article:16650762pubmed:articleTitleSynthesis and SAR of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives as non-peptidic motilin receptor antagonists.lld:pubmed
pubmed-article:16650762pubmed:affiliationJohnson & Johnson Pharmaceutical Research & Development, L.L.C., 1000 Rt. 202, PO Box 300, Raritan, NJ 08869, USA. sgjcej@juno.comlld:pubmed
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