| pubmed-article:1663006 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0061202 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0025663 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0042036 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0017110 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0022262 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0064971 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0079240 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0332257 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:1663006 | lifeskim:mentions | umls-concept:C0815051 | lld:lifeskim |
| pubmed-article:1663006 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1663006 | pubmed:dateCreated | 1992-2-27 | lld:pubmed |
| pubmed-article:1663006 | pubmed:abstractText | We describe an isotope dilution gas chromatographic-mass spectrometric method for the quantitative determination of the lignans enterolactone, enterodiol and matairesinol and the isoflavonoids daidzein, equol, O-desmethylangolensin and genistein in urine. Furthermore we present the gas chromatographic/mass spectrometer identification of genistein. Urine samples were extracted on Sep-Pak cartridges, conjugated fractions were isolated by chromatography on the acetate form of DEAE-Sephadex and deuterated internal standards of all seven compounds were added to the samples before hydrolysis. The hydrolysate was extracted on a Sep-Pak cartridge and following chromatography on the acetate form of QAE-Sephadex two fractions were obtained: Fraction 1 contained equol, enterolactone, enterodiol, matairesinol and all estrogens and fraction 2 contained O-desmethylangolensin, daidzein and genistein. The latter was ready for gas chromatography/mass spectrometry, but the first one was further purified to eliminate the estrogens by chromatography on the carbonate form of QAE-Sephadex. Following silylation, the samples were analyzed by combined capillary column gas chromatography/mass spectrometry in the selective ion monitoring mode. The within-assay imprecision varied from 0.8-15.2% (mean 8.7%) and the between-assay imprecision from 4.1-13.9% (mean 9.3%), depending on compound and concentration level. The mean recovery of authentic standards added to urine extracts before hydrolysis varied from 96.6 to 105.5%. Values obtained from 10 Finnish omnivorous men are presented. Individual values for matairesinol (excretion range 3.3-59.9 nmol/24 h) and genistein (range 21.8-1180 nmol/24 h) in human urine have never been published before. | lld:pubmed |
| pubmed-article:1663006 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1663006 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1663006 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1663006 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:1663006 | pubmed:issn | 0009-8981 | lld:pubmed |
| pubmed-article:1663006 | pubmed:author | pubmed-author:AdlercreutzHH | lld:pubmed |
| pubmed-article:1663006 | pubmed:author | pubmed-author:HastEE | lld:pubmed |
| pubmed-article:1663006 | pubmed:author | pubmed-author:FotsisTT | lld:pubmed |
| pubmed-article:1663006 | pubmed:author | pubmed-author:BannwartCC | lld:pubmed |
| pubmed-article:1663006 | pubmed:author | pubmed-author:WähäläKK | lld:pubmed |
| pubmed-article:1663006 | pubmed:author | pubmed-author:BrunowGG | lld:pubmed |
| pubmed-article:1663006 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1663006 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:1663006 | pubmed:volume | 199 | lld:pubmed |
| pubmed-article:1663006 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1663006 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1663006 | pubmed:pagination | 263-78 | lld:pubmed |
| pubmed-article:1663006 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:meshHeading | pubmed-meshheading:1663006-... | lld:pubmed |
| pubmed-article:1663006 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1663006 | pubmed:articleTitle | Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. | lld:pubmed |
| pubmed-article:1663006 | pubmed:affiliation | Department of Clinical Chemistry, University of Helsinki, Finland. | lld:pubmed |
| pubmed-article:1663006 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1663006 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1663006 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1663006 | lld:pubmed |
