| pubmed-article:1662691 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1662691 | lifeskim:mentions | umls-concept:C0021344 | lld:lifeskim |
| pubmed-article:1662691 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
| pubmed-article:1662691 | lifeskim:mentions | umls-concept:C0392918 | lld:lifeskim |
| pubmed-article:1662691 | lifeskim:mentions | umls-concept:C1511658 | lld:lifeskim |
| pubmed-article:1662691 | lifeskim:mentions | umls-concept:C1710548 | lld:lifeskim |
| pubmed-article:1662691 | lifeskim:mentions | umls-concept:C1522605 | lld:lifeskim |
| pubmed-article:1662691 | pubmed:dateCreated | 1992-2-20 | lld:pubmed |
| pubmed-article:1662691 | pubmed:abstractText | The non-coding region (NCR) of the epidermodysplasia verruciformis (EV)-associated human papillomavirus 8 (HPV-8) has been investigated for sequence-specific DNA-protein interactions with nuclear proteins from epithelial HeLa cells. Using DNase I protection analysis 18 footprints could be found within the HPV-8 NCR, covering altogether over 60% of both DNA strands. Several footprints coincided with the known binding sites of transcription factors (NF1, AP1, octamer and PEA3 consensus sequences); the other displayed no obvious similarities in this regard. The overall distribution of sequences involved in DNA-protein interactions differed clearly from the binding patterns reported for other HPVs. Parts of the two binding sites for the viral trans-activator protein E2 were shown to interact with non-E2 factors. The EV-specific NCR motifs M33, M29 and A/T box were all involved in protein binding. By comparing the footprints within the respective motifs of the closely related types HPV-8 and -19, quantitative and qualitative differences were detected for M33 and the A/T box. | lld:pubmed |
| pubmed-article:1662691 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1662691 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1662691 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1662691 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1662691 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1662691 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1662691 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:1662691 | pubmed:issn | 0022-1317 | lld:pubmed |
| pubmed-article:1662691 | pubmed:author | pubmed-author:PfisterHH | lld:pubmed |
| pubmed-article:1662691 | pubmed:author | pubmed-author:FuchsP GPG | lld:pubmed |
| pubmed-article:1662691 | pubmed:author | pubmed-author:MayMM | lld:pubmed |
| pubmed-article:1662691 | pubmed:author | pubmed-author:HelboSS | lld:pubmed |
| pubmed-article:1662691 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1662691 | pubmed:volume | 72 ( Pt 12) | lld:pubmed |
| pubmed-article:1662691 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1662691 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1662691 | pubmed:pagination | 2989-97 | lld:pubmed |
| pubmed-article:1662691 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:meshHeading | pubmed-meshheading:1662691-... | lld:pubmed |
| pubmed-article:1662691 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1662691 | pubmed:articleTitle | Unique topography of DNA-protein interactions in the non-coding region of epidermodysplasia verruciformis-associated human papillomaviruses. | lld:pubmed |
| pubmed-article:1662691 | pubmed:affiliation | Institut für Klinische und Molekulare Virologie, Friedrich-Alexander Universität Erlangen-Nürnberg, Germany. | lld:pubmed |
| pubmed-article:1662691 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1662691 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1662691 | lld:pubmed |
