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pubmed-article:16624831pubmed:abstractTextThe use of doxorubicin (DOX) as a chemotherapeutic agent is limited by cardiac injury. Iloprost, a stable synthetic analogue of prostacyclin, has previously been shown to protect against DOX-induced cardiomyocyte injury in vitro. Here, we addressed whether iloprost is cardioprotective in vivo and whether it compromises the anti-tumour efficacy of DOX.lld:pubmed
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pubmed-article:16624831pubmed:articleTitleIloprost attenuates doxorubicin-induced cardiac injury in a murine model without compromising tumour suppression.lld:pubmed
pubmed-article:16624831pubmed:affiliationDepartment of Clinical Pharmacology, Institute of Biopharmaceutical Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland. tneilan@partners.orglld:pubmed
pubmed-article:16624831pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16624831pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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