| pubmed-article:16610803 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C0003467 | lld:lifeskim |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C2936799 | lld:lifeskim |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C1373044 | lld:lifeskim |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C0449560 | lld:lifeskim |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C1879648 | lld:lifeskim |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C0205549 | lld:lifeskim |
| pubmed-article:16610803 | lifeskim:mentions | umls-concept:C0072677 | lld:lifeskim |
| pubmed-article:16610803 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:16610803 | pubmed:dateCreated | 2006-4-13 | lld:pubmed |
| pubmed-article:16610803 | pubmed:abstractText | The development of a series of GABA(A) alpha2/alpha3 subtype selective pyridazine based benzodiazepine site agonists as anxiolytic agents with reduced sedative/ataxic potential is described, including the discovery of 16, a remarkably alpha3-selective compound ideal for in vivo study. These ligands are antagonists at the alpha1 subtype, with good CNS penetration and receptor occupancy, and excellent oral bioavailability. | lld:pubmed |
| pubmed-article:16610803 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16610803 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16610803 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16610803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16610803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16610803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16610803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16610803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16610803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16610803 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16610803 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:16610803 | pubmed:issn | 0022-2623 | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:WaffordKeith... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:AtackJohn RJR | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:PikeAndrewA | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:SohalBindiB | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:ReynoldsDavid... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:StanleyJoanna... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:SmithAlison... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:CookSusan MSM | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:FerrisPushpin... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:WilsonRowan... | lld:pubmed |
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| pubmed-article:16610803 | pubmed:author | pubmed-author:TyeSpencer... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:SheppardWayne... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:HallettDavid... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:LewisRichard... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:MarshallGeorg... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:JenningsAndre... | lld:pubmed |
| pubmed-article:16610803 | pubmed:author | pubmed-author:BlackburnTimo... | lld:pubmed |
| pubmed-article:16610803 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16610803 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:16610803 | pubmed:volume | 49 | lld:pubmed |
| pubmed-article:16610803 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16610803 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16610803 | pubmed:pagination | 2600-10 | lld:pubmed |
| pubmed-article:16610803 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
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| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
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| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
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| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
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| pubmed-article:16610803 | pubmed:meshHeading | pubmed-meshheading:16610803... | lld:pubmed |
| pubmed-article:16610803 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16610803 | pubmed:articleTitle | A pyridazine series of alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety. | lld:pubmed |
| pubmed-article:16610803 | pubmed:affiliation | The Neuroscience Research Centre, Merck Sharp & Dohme Research Laboratories, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR, United Kingdom. richard_t_lewis@btinternet.com | lld:pubmed |
| pubmed-article:16610803 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:16610803 | lld:chembl |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16610803 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16610803 | lld:pubmed |
