| pubmed-article:16603216 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C0520503 | lld:lifeskim |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C1136102 | lld:lifeskim |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C0870432 | lld:lifeskim |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C1705417 | lld:lifeskim |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C1555465 | lld:lifeskim |
| pubmed-article:16603216 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:16603216 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16603216 | pubmed:dateCreated | 2006-5-22 | lld:pubmed |
| pubmed-article:16603216 | pubmed:abstractText | Expression of full-length and N-terminal deletion mutants of the coat protein (CP) of tomato bushy stunt virus (TBSV) using the recombinant baculovirus system resulted in spontaneously assembled virus-like particles (VLPs). Deletion of the majority of the R-domain sequence of the CP, residues 1-52 (CP-NDelta52) and 1-62 (CP-NDelta62), produced capsids similar to wild-type VLPs. Interestingly, the CP-NDelta62 mutant that retains the last 3 residues of R-domain is capable of forming both the T = 1 and T = 3 particles. However, between the two types of VLPs, formation of the T = 1 capsids appears to be preferred. Another mutant, CP-NDelta72, in which R-domain (residues 1-65) was completely removed but contains most of the beta-annulus and extended arm (betaA) regions exclusively formed T = 1 particles. These results suggest that as few as 3 residues (63-65) of the R-domain, which includes 2 basic amino acids together with the arm (betaA) and beta-annulus regions, may be sufficient for the formation of T = 3 particles. However, anywhere between 4 to 13 residues of the R-domain may be required for proper positioning of betaA and beta-annulus structural elements of the C-type subunits to facilitate an error free assembly of T = 3 capsids. | lld:pubmed |
| pubmed-article:16603216 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16603216 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16603216 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16603216 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16603216 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16603216 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16603216 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16603216 | pubmed:month | May | lld:pubmed |
| pubmed-article:16603216 | pubmed:issn | 0042-6822 | lld:pubmed |
| pubmed-article:16603216 | pubmed:author | pubmed-author:ManchesterMar... | lld:pubmed |
| pubmed-article:16603216 | pubmed:author | pubmed-author:SchneemannAne... | lld:pubmed |
| pubmed-article:16603216 | pubmed:author | pubmed-author:ReddyVijay... | lld:pubmed |
| pubmed-article:16603216 | pubmed:author | pubmed-author:SinghPratikP | lld:pubmed |
| pubmed-article:16603216 | pubmed:author | pubmed-author:OchoaWendyW | lld:pubmed |
| pubmed-article:16603216 | pubmed:author | pubmed-author:HsuCatherineC | lld:pubmed |
| pubmed-article:16603216 | pubmed:author | pubmed-author:ManayaniDarly... | lld:pubmed |
| pubmed-article:16603216 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16603216 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:16603216 | pubmed:volume | 349 | lld:pubmed |
| pubmed-article:16603216 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16603216 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16603216 | pubmed:pagination | 222-9 | lld:pubmed |
| pubmed-article:16603216 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:meshHeading | pubmed-meshheading:16603216... | lld:pubmed |
| pubmed-article:16603216 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16603216 | pubmed:articleTitle | Characterization of polymorphism displayed by the coat protein mutants of tomato bushy stunt virus. | lld:pubmed |
| pubmed-article:16603216 | pubmed:affiliation | Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. | lld:pubmed |
| pubmed-article:16603216 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16603216 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:16603216 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16603216 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16603216 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16603216 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16603216 | lld:pubmed |
