| pubmed-article:16601803 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16601803 | lifeskim:mentions | umls-concept:C0032343 | lld:lifeskim |
| pubmed-article:16601803 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:16601803 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:16601803 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:16601803 | lifeskim:mentions | umls-concept:C0001044 | lld:lifeskim |
| pubmed-article:16601803 | lifeskim:mentions | umls-concept:C0164843 | lld:lifeskim |
| pubmed-article:16601803 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:16601803 | pubmed:dateCreated | 2006-4-7 | lld:pubmed |
| pubmed-article:16601803 | pubmed:abstractText | The present study was performed to assess and compare a therapeutic efficacy of obidoxime, HI-6, BI-6 and HS-6 administered in equimolar doses and combined with atropine in cyclosarin-poisoned mice and rats. It was demonstrated that all the therapeutic regimens tested, were able to decrease the cyclosarin-induced toxicity significantly - at least 1.5 times. Higher therapeutic ratios, almost three times, were achieved in rats in comparison with mice. The highest therapeutic ratio was achieved for therapeutic regimen consisting of HI-6 and atropine in both mice and rats. Obidoxime was the least effective oxime in the treatment of cyclosarin intoxication. The BI-6 oxime was significantly more efficacious than obidoxime (in both mice and rats) and HS-6 (in rats) but its effectiveness did not reach the efficacy of HI-6. | lld:pubmed |
| pubmed-article:16601803 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16601803 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16601803 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16601803 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:16601803 | pubmed:issn | 1213-8118 | lld:pubmed |
| pubmed-article:16601803 | pubmed:author | pubmed-author:KucaKamilK | lld:pubmed |
| pubmed-article:16601803 | pubmed:author | pubmed-author:BartosováLuci... | lld:pubmed |
| pubmed-article:16601803 | pubmed:author | pubmed-author:KunesováGabri... | lld:pubmed |
| pubmed-article:16601803 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16601803 | pubmed:volume | 149 | lld:pubmed |
| pubmed-article:16601803 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16601803 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16601803 | pubmed:pagination | 425-7 | lld:pubmed |
| pubmed-article:16601803 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:meshHeading | pubmed-meshheading:16601803... | lld:pubmed |
| pubmed-article:16601803 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16601803 | pubmed:articleTitle | Effectivity of new acetylcholinesterase reactivators in treatment of cyclosarin poisoning in mice and rats. | lld:pubmed |
| pubmed-article:16601803 | pubmed:affiliation | Department of Toxicology, Faculty of Military Health Sciences, Hradec Králové, Czech Republic. bartosova@pmfhk.cz | lld:pubmed |
| pubmed-article:16601803 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16601803 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16601803 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
