pubmed-article:16556118 | pubmed:abstractText | There is a high incidence of hypophosphataemia in the critically ill. It is known that even moderate hypophosphataemia can produce a variety of adverse consequences. Many phosphate replacement regimens have been suggested, most are conservative and few validated in the critical care environment. We designed a study to determine the apparent volume of distribution of phosphate and quantify phosphate loss in critically ill patients following rapid phosphate infusion. With these data we sought to design a phosphate replacement protocol. | lld:pubmed |