| pubmed-article:16555088 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16555088 | lifeskim:mentions | umls-concept:C0017952 | lld:lifeskim |
| pubmed-article:16555088 | lifeskim:mentions | umls-concept:C0431085 | lld:lifeskim |
| pubmed-article:16555088 | lifeskim:mentions | umls-concept:C0242184 | lld:lifeskim |
| pubmed-article:16555088 | lifeskim:mentions | umls-concept:C0017725 | lld:lifeskim |
| pubmed-article:16555088 | lifeskim:mentions | umls-concept:C0162388 | lld:lifeskim |
| pubmed-article:16555088 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:16555088 | lifeskim:mentions | umls-concept:C0332206 | lld:lifeskim |
| pubmed-article:16555088 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:16555088 | pubmed:dateCreated | 2006-9-5 | lld:pubmed |
| pubmed-article:16555088 | pubmed:abstractText | Since 2-deoxy-D-glucose (2-DG) is currently in phase I clinical trials to selectively target slow-growing hypoxic tumor cells, 2-halogenated D-glucose analogs were synthesized for improved activity. Given the fact that 2-DG competes with D-glucose for binding to hexokinase, in silico modeling of molecular interactions between hexokinase I and these new analogs was used to determine whether binding energies correlate with biological effects, i.e. inhibition of glycolysis and subsequent toxicity in hypoxic tumor cells. | lld:pubmed |
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| pubmed-article:16555088 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16555088 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16555088 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16555088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16555088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16555088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16555088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16555088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16555088 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16555088 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:16555088 | pubmed:issn | 0344-5704 | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:KrishanAwtarA | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:GinalskiKrzys... | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:PriebeWaldema... | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:FoktIzabelaI | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:LiuHuapingH | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:LampidisTheod... | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:RudnickiWitol... | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:MaherJohnatha... | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:SzymanskiSlaw... | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:KurtogluMetin... | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:SheftValerieV | lld:pubmed |
| pubmed-article:16555088 | pubmed:author | pubmed-author:LesyngBogdanB | lld:pubmed |
| pubmed-article:16555088 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16555088 | pubmed:volume | 58 | lld:pubmed |
| pubmed-article:16555088 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16555088 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16555088 | pubmed:pagination | 725-34 | lld:pubmed |
| pubmed-article:16555088 | pubmed:dateRevised | 2007-12-3 | lld:pubmed |
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| pubmed-article:16555088 | pubmed:meshHeading | pubmed-meshheading:16555088... | lld:pubmed |
| pubmed-article:16555088 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16555088 | pubmed:articleTitle | Efficacy of 2-halogen substituted D-glucose analogs in blocking glycolysis and killing "hypoxic tumor cells". | lld:pubmed |
| pubmed-article:16555088 | pubmed:affiliation | School of Medicine and Sylvester Cancer Center, The University of Miami, Miami, FL, USA. | lld:pubmed |
| pubmed-article:16555088 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16555088 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16555088 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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