pubmed-article:16517222 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16517222 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:16517222 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
pubmed-article:16517222 | lifeskim:mentions | umls-concept:C0024868 | lld:lifeskim |
pubmed-article:16517222 | lifeskim:mentions | umls-concept:C0009073 | lld:lifeskim |
pubmed-article:16517222 | pubmed:issue | 1-2 | lld:pubmed |
pubmed-article:16517222 | pubmed:dateCreated | 2006-4-17 | lld:pubmed |
pubmed-article:16517222 | pubmed:abstractText | An analytical procedure was developed and validated for the quantification of clotiazepam in human plasma. After subjecting plasma samples to solid-phase extraction, the extract was evaporated and the residue re-constituted. An aliquot of the mixture was injected onto a gas chromatography-mass spectrometry system. The detector response was linear for clotiazepam concentrations in the range of 5-200 ng/ml. Intra- and inter-day precision for the assay over the concentration range was below 13.1 and 13.5%, and the accuracy ranged between 99.0-107.9% and 92.4-101.3%, respectively. The drug was found to be stable under various processing conditions used. The method is applicable to human pharmacokinetic studies of clotiazepam. | lld:pubmed |
pubmed-article:16517222 | pubmed:language | eng | lld:pubmed |
pubmed-article:16517222 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16517222 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16517222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16517222 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16517222 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16517222 | pubmed:month | Apr | lld:pubmed |
pubmed-article:16517222 | pubmed:issn | 1570-0232 | lld:pubmed |
pubmed-article:16517222 | pubmed:author | pubmed-author:ChungSuk-JaeS... | lld:pubmed |
pubmed-article:16517222 | pubmed:author | pubmed-author:ShimChang-Koo... | lld:pubmed |
pubmed-article:16517222 | pubmed:author | pubmed-author:KimDae-DukDD | lld:pubmed |
pubmed-article:16517222 | pubmed:author | pubmed-author:AhnSung-HoonS... | lld:pubmed |
pubmed-article:16517222 | pubmed:author | pubmed-author:MaengHan-JooH... | lld:pubmed |
pubmed-article:16517222 | pubmed:author | pubmed-author:KooTae-SungTS | lld:pubmed |
pubmed-article:16517222 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16517222 | pubmed:day | 13 | lld:pubmed |
pubmed-article:16517222 | pubmed:volume | 834 | lld:pubmed |
pubmed-article:16517222 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16517222 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16517222 | pubmed:pagination | 128-33 | lld:pubmed |
pubmed-article:16517222 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:16517222 | pubmed:meshHeading | pubmed-meshheading:16517222... | lld:pubmed |
pubmed-article:16517222 | pubmed:meshHeading | pubmed-meshheading:16517222... | lld:pubmed |
pubmed-article:16517222 | pubmed:meshHeading | pubmed-meshheading:16517222... | lld:pubmed |
pubmed-article:16517222 | pubmed:meshHeading | pubmed-meshheading:16517222... | lld:pubmed |
pubmed-article:16517222 | pubmed:meshHeading | pubmed-meshheading:16517222... | lld:pubmed |
pubmed-article:16517222 | pubmed:meshHeading | pubmed-meshheading:16517222... | lld:pubmed |
pubmed-article:16517222 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16517222 | pubmed:articleTitle | Quantification of clotiazepam in human plasma by gas chromatography-mass spectrometry. | lld:pubmed |
pubmed-article:16517222 | pubmed:affiliation | Department of Pharmaceutics, College of Pharmacy, Seoul National University, San 56-1, Shinlim-dong, Kwanak-gu, 151-742, South Korea. | lld:pubmed |
pubmed-article:16517222 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:16517222 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:16517222 | pubmed:publicationType | Validation Studies | lld:pubmed |