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pubmed-article:16510745pubmed:abstractTextInterferon beta is used to modify the course of relapsing multiple sclerosis. Despite interferon beta therapy, many patients have relapses. Natalizumab, an alpha4 integrin antagonist, appeared to be safe and effective alone and when added to interferon beta-1a in preliminary studies.lld:pubmed
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pubmed-article:16510745pubmed:articleTitleNatalizumab plus interferon beta-1a for relapsing multiple sclerosis.lld:pubmed
pubmed-article:16510745pubmed:affiliationMellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. rudickr@ccf.orglld:pubmed
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