Tropical pyomyositis is very rarely associated with rheumatoid arthritis. We report tropical pyomyositis involving gastrocnemius muscle in both the legs with eosinophilia and elevated serum IgG and IgE levels in a case of rheumatoid arthritis. We suggest that the possibility of pyomyositis should be considered in all cases of rheumatoid arthritis presenting with muscle pain, fever and leucocytosis.