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pubmed-article:164696pubmed:abstractTextThe powerful nuclear medicine tool of radioimmunoassay was very rapidly developed because of the favorable properties of insulin in such a procedure. The current method of insulin immunoassay in our laboratory is described, with emphasis on the details of the separation of bound and free using talc tablets; emphasis is also given to the correction for tracer damage. The clinical usefulness of the insulin radioimmunoassay is somewhat less than had been anticipated, although its use as a research tool has had immeasurable impact upon the study of metabolism. The presence of proinsulin in plasma is a factor that has to be considered during the radioimmunoassay. Radioimmunoassays for the connecting peptide of proinsulin have also been developed. A preliminary evaluation of two radioimmunoassay kits is described.lld:pubmed
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pubmed-article:164696pubmed:pagination183-8lld:pubmed
pubmed-article:164696pubmed:dateRevised2011-11-17lld:pubmed
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pubmed-article:164696pubmed:year1975lld:pubmed
pubmed-article:164696pubmed:articleTitleRadioimmunoassay of insulin.lld:pubmed
pubmed-article:164696pubmed:publicationTypeJournal Articlelld:pubmed