pubmed-article:16468724 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C0002068 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C0012512 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C1420100 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C0182400 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
pubmed-article:16468724 | lifeskim:mentions | umls-concept:C0070351 | lld:lifeskim |
pubmed-article:16468724 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:16468724 | pubmed:dateCreated | 2006-2-10 | lld:pubmed |
pubmed-article:16468724 | pubmed:abstractText | [reaction: see text] Described is a novel synthetic route for dipeptide isosteres containing (Z)-alkene and (E)-fluoroalkene units as cis-amide bond equivalents via organocopper-mediated reduction of gamma-acetoxy- or gamma,gamma-difluoro-alpha,beta-unsaturated-delta-lactams. The synthesized isosteres were evaluated in terms of their affinities for the peptide transporter PEPT1. trans-Amide isosteres tended to possess higher affinities for PEPT1 as compared to the corresponding cis-amide bond equivalents. | lld:pubmed |
pubmed-article:16468724 | pubmed:language | eng | lld:pubmed |
pubmed-article:16468724 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16468724 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16468724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16468724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16468724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16468724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16468724 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16468724 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16468724 | pubmed:month | Feb | lld:pubmed |
pubmed-article:16468724 | pubmed:issn | 1523-7060 | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:InuiKen-ichiK | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:OishiShinyaS | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:FujiiNobutaka... | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:OtakaAkiraA | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:NiidaAyumuA | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:TeradaTomohir... | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:MizumotoMakik... | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:TomitaKenjiK | lld:pubmed |
pubmed-article:16468724 | pubmed:author | pubmed-author:TanigakiHiroa... | lld:pubmed |
pubmed-article:16468724 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16468724 | pubmed:day | 16 | lld:pubmed |
pubmed-article:16468724 | pubmed:volume | 8 | lld:pubmed |
pubmed-article:16468724 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16468724 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16468724 | pubmed:pagination | 613-6 | lld:pubmed |
pubmed-article:16468724 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:16468724 | pubmed:meshHeading | pubmed-meshheading:16468724... | lld:pubmed |
pubmed-article:16468724 | pubmed:meshHeading | pubmed-meshheading:16468724... | lld:pubmed |
pubmed-article:16468724 | pubmed:meshHeading | pubmed-meshheading:16468724... | lld:pubmed |
pubmed-article:16468724 | pubmed:meshHeading | pubmed-meshheading:16468724... | lld:pubmed |
pubmed-article:16468724 | pubmed:meshHeading | pubmed-meshheading:16468724... | lld:pubmed |
pubmed-article:16468724 | pubmed:meshHeading | pubmed-meshheading:16468724... | lld:pubmed |
pubmed-article:16468724 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16468724 | pubmed:articleTitle | Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1. | lld:pubmed |
pubmed-article:16468724 | pubmed:affiliation | Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. | lld:pubmed |
pubmed-article:16468724 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:16468724 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16468724 | lld:pubmed |