| pubmed-article:16466462 | pubmed:abstractText | The suitability of passive telemetry for long-term measurements of gastric motility in two groups of dogs with different body weights, four Beagles and four Labrador Retrievers, was investigated. An intra-abdominal measuring device, with a pressure sensor and electrodes within the gastric wall, allowed the continuous recording of the intensity and frequency of contractions simultaneously with an electromyogram (EMG). In fasting dogs a typical inter-digestive motility cycle was reproducible. Within 15 min of feeding the integral of the pressure curve increased significantly, reaching its maximum 30-45 min post-prandially. The peak frequency also significantly increased immediately after feeding, reaching the maximum of 22 contractions per 5 min. The post-prandial motility patterns of the groups were significantly different. The pressure amplitudes of the Labradors were significantly higher and the peak frequencies significantly lower than the Beagles. The addition of guar to the food (2.5% or 5%) leads to a significant reduction of the intensity of the antral contractions, whereas the frequency was hardly affected. In comparison, the effect of cellulose, as a food additive (2.5% or 5%), was rather modest. The intensity of the post-prandial contractions, influenced by cellulose, was significantly increased in Beagles, but was decreased in Labradors. Passive telemetry has been proven to be a suitable method for the long-term investigation of the physiological gastric motility and the effect of food additives. The measuring device was still functional after removal 8 weeks later. | lld:pubmed |
