pubmed-article:16445833 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16445833 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:16445833 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
pubmed-article:16445833 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
pubmed-article:16445833 | lifeskim:mentions | umls-concept:C2917212 | lld:lifeskim |
pubmed-article:16445833 | lifeskim:mentions | umls-concept:C0086969 | lld:lifeskim |
pubmed-article:16445833 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
pubmed-article:16445833 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
pubmed-article:16445833 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:16445833 | pubmed:dateCreated | 2006-1-31 | lld:pubmed |
pubmed-article:16445833 | pubmed:abstractText | Several studies suggest that patient self-management (PSM) may improve the quality of oral anticoagulation therapy as measured by time spent within the international normalised ratio (INR) target range. We performed a prospective randomised control trial to determine whether the improvement in quality of treatment afforded by PSM is greater than that achieved by patient self-testing (PST) alone. A total of 104 of 800 eligible patients aged 22-88 years (median = 59.8), attending our hospital anticoagulant clinic and receiving long-term warfarin for >8 months agreed to participate. Patients were randomised to PSM (n = 55) or PST (n = 49). Both groups measured their INR using the CoaguChek S every 2 weeks or more frequently if required, for a period of 6 months. Seventy-seven of 104 (74%) patients completed the study (PSM = 41 and PST = 36). The 'drop out' rates for both groups were similar. There was no significant difference between the percentage time in target therapeutic range for PSM (69.9%) and PST (71.8%). Both groups combined showed a significant improvement over the previous 6 months (71.0% vs. 62.5%; P = 0.04). Changes in time within the therapeutic range in individual patients (+5.86) also showed a significant difference. The quality of warfarin control in both PST and PSM may be superior to that achieved by conventional management in a specialised hospital anticoagulation clinic. | lld:pubmed |
pubmed-article:16445833 | pubmed:language | eng | lld:pubmed |
pubmed-article:16445833 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16445833 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16445833 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16445833 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16445833 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16445833 | pubmed:month | Mar | lld:pubmed |
pubmed-article:16445833 | pubmed:issn | 0007-1048 | lld:pubmed |
pubmed-article:16445833 | pubmed:author | pubmed-author:CohenHannahH | lld:pubmed |
pubmed-article:16445833 | pubmed:author | pubmed-author:MackieIan JIJ | lld:pubmed |
pubmed-article:16445833 | pubmed:author | pubmed-author:MachinSamuel... | lld:pubmed |
pubmed-article:16445833 | pubmed:author | pubmed-author:WilliamsKaren... | lld:pubmed |
pubmed-article:16445833 | pubmed:author | pubmed-author:GardinerChris... | lld:pubmed |
pubmed-article:16445833 | pubmed:author | pubmed-author:LongairIanI | lld:pubmed |
pubmed-article:16445833 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16445833 | pubmed:volume | 132 | lld:pubmed |
pubmed-article:16445833 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16445833 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16445833 | pubmed:pagination | 598-603 | lld:pubmed |
pubmed-article:16445833 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:16445833 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16445833 | pubmed:articleTitle | A randomised control trial of patient self-management of oral anticoagulation compared with patient self-testing. | lld:pubmed |
pubmed-article:16445833 | pubmed:affiliation | Department of Haematology, University College London Hospitals, London, UK. chris.gardiner@uchevaluation.co.uk | lld:pubmed |
pubmed-article:16445833 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:16445833 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
pubmed-article:16445833 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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