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pubmed-article:16441796pubmed:abstractText. Proton pump inhibitors are currently used widely for the treatment of laryngopharyngeal reflux. . This systematic review assessed the efficacy of proton pump inhibitors in the treatment of symptoms of laryngopharyngeal reflux. . Outcome measures used to assess efficacy of proton pump inhibitors included endoscopic laryngeal signs and pH recordings. .Only two small randomized-controlled trials included patients with objective evidence of reflux in the 24-h ambulatory oesophageal pH monitoring. . Pooled analysis of these two randomized-controlled trials failed to show any effect in favour of treatment with proton pump inhibitors. .Further randomized-controlled trials are required to ascertain the role of proton pump inhibitors in the treatment of laryngopharyngeal reflux.lld:pubmed
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pubmed-article:16441796pubmed:pagination20-4; discussion 24lld:pubmed
pubmed-article:16441796pubmed:dateRevised2009-11-3lld:pubmed
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pubmed-article:16441796pubmed:articleTitleA systematic review of the role of proton pump inhibitors for symptoms of laryngopharyngeal reflux.lld:pubmed
pubmed-article:16441796pubmed:affiliationDepartment of Otolaryngology and Head and Neck Surgery, Whipps Cross University Hospital, London, UK. senswathi@aol.comlld:pubmed
pubmed-article:16441796pubmed:publicationTypeJournal Articlelld:pubmed
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