pubmed-article:16412088 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16412088 | lifeskim:mentions | umls-concept:C0012737 | lld:lifeskim |
pubmed-article:16412088 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
pubmed-article:16412088 | lifeskim:mentions | umls-concept:C1158770 | lld:lifeskim |
pubmed-article:16412088 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:16412088 | pubmed:dateCreated | 2006-1-17 | lld:pubmed |
pubmed-article:16412088 | pubmed:abstractText | This study demonstrates that cDNA-AFLP is a powerful gel-based genome-scale transcript profiling technique to generate quantitative gene expression profiles for eQTL mapping. We used cDNA-AFLP to monitor the relative abundance of 912 transcripts across 50 Arabidopsis thaliana recombinant inbred lines. Estimates for heritability of cDNA-AFLP intensity polymorphisms were high, with a median of 0.30 and an interquartile range of 0.21-0.44. A total of 198 expression polymorphisms were significantly linked to specific chromosomal regions (P < 0.05). Both cis- and trans-acting loci correlated with the variation in gene expression levels were found. Some of the trans-acting loci correlated to multiple expression polymorphisms, suggesting trans-acting alleles with widespread transcriptional effects. Here, we have illustrated that cDNA-AFLP constitutes a powerful transcript profiling method that can be utilized for 'multifactorial genomics' analysis of any plant or animal species for which segregating populations and molecular marker maps are available. | lld:pubmed |
pubmed-article:16412088 | pubmed:language | eng | lld:pubmed |
pubmed-article:16412088 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16412088 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16412088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16412088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16412088 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16412088 | pubmed:month | Feb | lld:pubmed |
pubmed-article:16412088 | pubmed:issn | 0960-7412 | lld:pubmed |
pubmed-article:16412088 | pubmed:author | pubmed-author:ZabeauMarcM | lld:pubmed |
pubmed-article:16412088 | pubmed:author | pubmed-author:VuylstekeMarn... | lld:pubmed |
pubmed-article:16412088 | pubmed:author | pubmed-author:KuiperMartinM | lld:pubmed |
pubmed-article:16412088 | pubmed:author | pubmed-author:DaeleHildeH | lld:pubmed |
pubmed-article:16412088 | pubmed:author | pubmed-author:VercauterenAn... | lld:pubmed |
pubmed-article:16412088 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16412088 | pubmed:volume | 45 | lld:pubmed |
pubmed-article:16412088 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16412088 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16412088 | pubmed:pagination | 439-46 | lld:pubmed |
pubmed-article:16412088 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:16412088 | pubmed:meshHeading | pubmed-meshheading:16412088... | lld:pubmed |
pubmed-article:16412088 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16412088 | pubmed:articleTitle | Genetic dissection of transcriptional regulation by cDNA-AFLP. | lld:pubmed |
pubmed-article:16412088 | pubmed:affiliation | Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University, Technologiepark 927, B9052 Gent, Belgium. marnik.vuylsteke@psb.ugent.be | lld:pubmed |
pubmed-article:16412088 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:16412088 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:16412088 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
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