| pubmed-article:16404154 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16404154 | lifeskim:mentions | umls-concept:C0035567 | lld:lifeskim |
| pubmed-article:16404154 | lifeskim:mentions | umls-concept:C0012655 | lld:lifeskim |
| pubmed-article:16404154 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:16404154 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:16404154 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
| pubmed-article:16404154 | lifeskim:mentions | umls-concept:C0337026 | lld:lifeskim |
| pubmed-article:16404154 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:16404154 | pubmed:dateCreated | 2006-1-11 | lld:pubmed |
| pubmed-article:16404154 | pubmed:abstractText | As a first step towards identifying genes involving in the signal transduction pathways mediating rice blast resistance, we isolated 3 mutants lines that showed enhanced susceptibility to rice blast KJ105 (91-033) from a T-DNA insertion library of the japonica rice cultivar, Hwayeong. Since none of the susceptible phenotypes co-segregated with the T-DNA insertion we adapted a map-based cloning strategy to isolate the gene(s) responsible for the enhanced susceptibility of the Hwayeong mutants. A genetic mapping population was produced by crossing the resistant wild type Hwayeong with the susceptible cultivar, Nagdong. Chi-square analysis of the F2 segregating population indicated that resistance in Hwayeong was controlled by a single major gene that we tentatively named Pi-hy. Randomly selected susceptible plants in the F2 population were used to build an initial map of Pi-hy. The SSLP marker RM2265 on chromosome 2 was closely linked to resistance. High resolution mapping using 105 F2 plants revealed that the resistance gene was tightly linked, or identical, to Pib, a resistance gene with a nucleotide binding sequence and leucine-rich repeats (NB-LRR) previously isolated. Sequence analysis of the Pib locus amplified from three susceptible mutants revealed lesions within this gene, demonstrating that the Pi-hy gene is Pib. The Pib mutations in 1D-22-10-13, 1D-54-16-8, and 1C-143-16-1 were, respectively, a missense mutation in the conserved NB domain 3, a nonsense mutation in the 5th LRR, and a nonsense mutation in the C terminus following the LRRs that causes a small deletion of the C terminus. These findings provide evidence that NB domain 3 and the C terminus are required for full activity of the plant R gene. They also suggest that alterations of the resistance gene can cause major differences in pathogen specificity by affecting interactions with an avirulence factor. | lld:pubmed |
| pubmed-article:16404154 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16404154 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16404154 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16404154 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16404154 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16404154 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16404154 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16404154 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16404154 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16404154 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:16404154 | pubmed:issn | 1016-8478 | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:KimHye-KyungH... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:AnGynheungG | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:LeeSang-KyuSK | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:HahnTae-Ryong... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:LeeYoun-Hyung... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:JwaNam-SooNS | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:LeeSichulS | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:JeonJong-Seon... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:ChoJung-IlJI | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:YiGihwanG | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:KimByung-Ryun... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:ChoYoung-Chan... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:HanSeong-Sook... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:BhooSeong-Hee... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:HongYeon-KyuY... | lld:pubmed |
| pubmed-article:16404154 | pubmed:author | pubmed-author:ParkDae-SupDS | lld:pubmed |
| pubmed-article:16404154 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16404154 | pubmed:day | 31 | lld:pubmed |
| pubmed-article:16404154 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:16404154 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16404154 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16404154 | pubmed:pagination | 385-91 | lld:pubmed |
| pubmed-article:16404154 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:meshHeading | pubmed-meshheading:16404154... | lld:pubmed |
| pubmed-article:16404154 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16404154 | pubmed:articleTitle | Characterization of rice mutants with enhanced susceptibility to rice blast. | lld:pubmed |
| pubmed-article:16404154 | pubmed:affiliation | Plant Metabolism Research Center and Graduate School of Biotechnology, Kyung Hee University, Yongin 449-701, Korea. | lld:pubmed |
| pubmed-article:16404154 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16404154 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
